A paper by: Dr. Abdur-Rafay Shareef, Chemist, USFDA, United States; Zhichao Lin, Office of Regulatory Affairs (ORA), Winchester Engineering and Analytical Center (WEAC), USA; Stephanie Healey, Office of Regulatory Affairs (ORA), Winchester Engineering and Analytical Center (WEAC), USA; Patrick Regan, Office of Regulatory Affairs (ORA), Winchester Engineering and Analytical Center (WEAC), USA; Brian Baker, Office of Regulatory Affairs (ORA), Winchester Engineering and Analytical Center (WEAC), USA; William Cunningham, Center for Food Safety and Applied Nutrition (CFSAN), Office of Regulator Science (ORS), USA

The US Food and Drug Administration (FDA) has excellent capability for monitoring food for radionuclide contamination. However, the current methods available for alpha- and beta-emitting radionuclides are limited because they are time consuming with multi-day procedures often required to isolate them from sample matrix and interfering radionuclides. In the aftermath of an accident involving nuclear-energy or -weapon materials, the US FDA could be tasked with monitoring the food supply for this type of contamination. Our research goal is to develop rapid and high-throughput methods for these radionuclides in foods. Our initial application will be the detection of processed uranium in foods using isotope ratio mass spectrometry (IR-MS). Although uranium is a naturally-occurring radionuclide, processed uranium has nuclear weapons and energy applications whereby its natural isotopic ratio of 238 U/235U has been altered for its intended uses. The natural 238U/235U ratio is 137.82 ± 0.21 (1s) but this ratio is much greater for processed uranium. For example energy grade uranium contains 3 – 5% of 235U, and weapons grade uranium contains >90% of 235U. The IR-MS method is capable of revealing uranium source term via accurate and precise measurement of 238U/235U ratio. This project is intended to further improve the US FDA’s radioanalytical capacity for monitoring radioactive food contamination.

Please access the Full Paper by clicking on the following link: Shareef – NCT CBRNe USA 2015

The Full Paper by Shareef, Lin, Healey, Regan, Baker will be presented during NCT CBRNe USA Innovation Stream, taking place from April 29 to May 1.

 

Join us in NCT CBRNe USA 2015 to learn and discuss about this paper and other innovative ideas by registering now!